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The efficacy and function of Zhiyuanzhi
2026-09-20 16:42:25
Overview of the efficacy and functions of Zhiyuanzhi
Polygala Polygala is a commonly used medicine in traditional Chinese medicine to calm the nerves and improve intelligence. It is prepared from Polygala Polygala. It hasCalming the mind, relieving phlegm and resuscitation, dissipating carbuncleThe three core functions are mainly used for symptoms such as restlessness, insomnia and forgetfulness, phlegm blocking the heart orifices, and sores, swelling and pain.Modern research shows that its active ingredients regulate the central nervous system and improve cognitive function.The following will start with traditional applications, pharmacological mechanisms and precautions, and systematically analyze its value and reasonable usage.
1. Traditional effects: dual effects of calming the nerves and resolving phlegm

Zhiyuanzhi is listed as top grade in "Shen Nong's Materia Medica", emphasizing its "Strong Zhibili"The effect.Traditional Chinese medicine believes that it is slightly warm in nature and can be directed to the heart, kidney, and lung meridians. It can not only calm the mind, relieve anxiety and insomnia, but also resolve mental confusion or cough with excessive phlegm caused by phlegm and dampness.For example, "Anshen Dingzhi Wan", which is combined with Ziziphus seeds and Poria cocos, is a classic prescription for treating insomnia caused by heart-kidney disharmony.In addition, its phlegm-reducing effect is also helpful in the recovery of phlegm-obscured Xinqiao after epilepsy and stroke.
2. Modern pharmacology: scientific verification from ingredients to mechanism
Research has found that Zhiyuan Zhi containsPolygala saponin, Polygala ketoneand other ingredients, can enhance the level of acetylcholine in the brain and improve memory disorders (see table).Animal experiments show that its extract can prolong sleep time and inhibit inflammatory factors, confirming the traditional effect of "dispersing carbuncles".However, it should be noted that overdose may cause nausea, so it is recommended to control the dosage according to your doctor's advice.
| Ingredients | function | References |
|---|---|---|
| Polygala saponin B | Improve memory and fight anxiety | "Chinese Herbal Medicine" 2018 |
| Polygalone III | Anti-inflammatory, neuroprotective | "Journal of Pharmaceutical Sciences" 2020 |
3. Applicable groups and taboos: the key to dialectical use
Zhiyuanzhi is suitable forHeart and spleen deficiencyIt is suitable for insomniacs, people with phlegm-dampness constitution and people who need cognitive recovery after surgery, but it should be used with caution by those with yin deficiency and excessive fire.Pregnant women and patients with gastritis should avoid excessive use of single flavor.It is clinically recommended to take 3-10 grams per day in decoction or pill form.When used externally to treat sores and ulcers, you can grind it into powder and mix it with vinegar, but you need to prevent allergies.
4. Summary: Reasonable use can be effective
As a medicinal material with both traditional and modern values, Zhiyuanzhi has a clear effect of calming the nerves and reducing phlegm, but it needs to be used in combination with physical constitution and symptom differentiation.Scientific compatibility (such as cinnabar to calm convulsions, Platycodon to relieve the lungs) can enhance efficacy and reduce toxicity.Future research may further explore its potential in neurodegenerative diseases.
Quote sources:
1. "Chinese Pharmacopoeia" 2020 Edition (National Pharmacopoeia Commission)
2. Analysis of Polygala compatibility prescriptions in Zhang Zhongjing's "Synopsis of the Golden Chamber"
3. Polygala entries in Li Shizhen's "Compendium of Materia Medica"
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