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The efficacy and function of Yiguanjian
2026-04-24 08:58:29
Overview of the efficacy and functions of Yiguijian
Yiguanjian is a classic prescription of traditional Chinese medicine. Its main function is to nourish yin and soothe the liver. It is often used to treat liver and kidney yin deficiency and liver-qi discomfort. Its core functions includeNourishes liver yin, reconciles liver qi, and relieves hypochondriac pain, supplemented by it to improve accompanying symptoms such as dry mouth and throat, insomnia and dreaminess. In the prescription, Rehmannia glutinosa is reused as the king medicine, and it is combined with yin-nourishing medicinal materials such as Adenophora adenophora and Ophiopogon japonicus, as well as Sophora azadirachta to soothe the liver and regulate qi, forming a compatibility characteristic of "tonifying the middle and sparing". The following will start with its formulation principle, applicable population, clinical application and precautions, and systematically analyze the value of this prescription.
Formula principle and efficacy analysis

Always fried byRaw Rehmannia glutinosa, Adenophora adenophora, Ophiopogon japonicus, Angelica sinensis, Lycium barbarum, Sophora indica.It is composed of six herbs, which are based on nourishing yin and nourishing blood, and also take care of soothing and releasing liver qi. Rehmannia glutinosa nourishes kidney yin and is the king; Adenophora adenophora and Ophiopogon japonicus moisten the lungs and nourish yin, and help rehmannia glutinosa replenish water and control fire; Angelica sinensis and wolfberry nourish liver blood and soften the liver body; Melanium azadirachta soothes the liver and promotes qi, preventing stagnation with yin-nourishing drugs. The whole formula embodies the theory of "liver body yin and uses yang", which not only replenishes liver yin deficiency, but also regulates stagnation of liver qi, which is especially suitable forHypochondriac pain due to yin deficiency and liver stagnation, manifested by symptoms such as dull pain in the hypochondrium, dry throat, red tongue, stringy and thready pulse.
Applicable groups and typical symptoms
Yiguijian mainly targetsLong-term moodiness, staying up too late, or chronic illness deplete yin fluidscrowd. Typical indications include: flank pain or burning pain (common in chronic hepatitis and cholecystitis), dizziness, irritability, night sweats, etc. In modern clinical practice, it is also used for menopausal syndrome, hyperthyroidism, and other patients with yin deficiency and liver hyperactivity. It should be noted that people with spleen and stomach deficiency should use it with caution. The eucalyptus in the recipe is slightly toxic and needs to be strictly controlled. The following is a comparison table of commonly applicable symptoms:
| Symptoms | TCM syndrome differentiation | modern disease associations |
|---|---|---|
| Dull pain in flank | Insufficient liver yin and loss of nourishment of collaterals | Chronic hepatitis, intercostal neuralgia |
| dry mouth | Body fluid deficiency | Diabetes, Sjögren's syndrome |
| Insomnia and dreaminess | False fire disturbs the gods | neurasthenia, menopause |
Clinical applications and precautions
Use consistent frying requirementsAccurate diagnosis, cannot be abused. In clinical practice, additions and subtractions are often used: if the spleen and stomach are weak, add Atractylodes macrocephala and Poria cocos; for hot flashes, add Digupi; for severe qi depression, add Cyperus rotunda. It is necessary to avoid taking it with spicy, warm and dry food, and avoid being angry or depressed while taking the medicine. Modern research shows that its active ingredients can regulate liver microcirculation and inhibit fibrosis (refer to "Pharmacology and Application of Traditional Chinese Medicine"), but it must be used under the guidance of a physician and cannot be taken by oneself for a long time.
Summary and scientific understanding
Yiguanjian is a representative prescription of the "nourishing yin and soothing the liver" method of traditional Chinese medicine. It has clear effects on specific constitutions (yin deficiency and liver stagnation), but it is not a universal health product. Its value lies inTaking into account both specimens and specimensThe wisdom of formulating the formula is not just "tonifying the liver". Patients should combine modern examinations to determine the cause. For example, hepatitis B virus carriers need to cooperate with antiviral treatment. Only by correctly understanding its "regulating" rather than "replacing" role can the advantages of traditional medicine be brought into play.
Citing sources
1. "Traditional Chinese Medicine Prescriptions" People's Medical Publishing House, Editor-in-Chief: Deng Zhongjia
2. "Pharmacology and Application of Traditional Chinese Medicine" China Traditional Chinese Medicine Press, data reference: Wang Benxiang's research group
3. For the key points of clinical syndrome differentiation, please refer to "Traditional Chinese Medicine Internal Medicine" written by Zhou Zhongying
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