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Four things soup
2026-03-21 12:39:33
Siwu Decoction: Analysis and application of traditional famous prescriptions for nourishing blood and regulating menstruation.
Siwu Decoction is a classic blood-nourishing prescription of traditional Chinese medicine.Angelica sinensis, Chuanxiong rhizome, white peony root, rehmannia glutinosaComposed of four medicinal materials, it is mainly used to nourish blood, activate blood circulation, regulate menstruation and relieve pain. It is widely used for blood deficiency syndrome and gynecological conditioning. This article will start from four levels: the formulation principle, efficacy breakdown, applicable groups and modern applications, supplemented by data comparison, to systematically interpret the scientific value and practical significance of this thousand-year-old prescription.
1. Principle of prescription and compatibility of medicinal materials

Four things soup"Replenishes blood without leaving blood stasis, promotes blood circulation without damaging blood"As the core concept, the four medicines each perform their own duties: Rehmannia glutinosa nourishes yin and nourishes blood as the emperor, Angelica sinensis nourishes blood and activates blood circulation as the minister, white peony root nourishes blood and softens the liver as the assistant, and Ligusticum chuanxiong activates blood and promotes qi as the envoy. This combination creates a balance of "tonifying and stimulating, calming and moving", which is especially suitable for people with blood deficiency and blood stagnation. According to the "Taiping Huimin Heji Bureau Prescription", the original dosage of the prescription is 12g of Rehmannia glutinosa, 9g of Angelica sinensis, 9g of white peony root, and 6g of Chuanxiong. In modern clinical practice, the dosage is often modified according to physical constitution.
2. Efficacy breakdown and indication analysis
The core functions of Siwu Decoction can be summarized into three categories:Replenish blood(Improve pale complexion, dizziness and palpitations),Regulate menstruation(Relieves low menstrual flow, dysmenorrhea, and amenorrhea),Nourish the liver(Regulate mood swings and swelling). Modern research shows that its active ingredients (such as ferulic acid, paeoniflorin) can promote the proliferation of hematopoietic stem cells (see Table 1). It should be noted that people with yin deficiency and fire hyperactivity or damp-heat constitution need to use it in conjunction with heat-clearing medicine to avoid aggravating heat symptoms when taken alone.
| Medicinal materials | active ingredients | Pharmacological effects |
|---|---|---|
| Angelica sinensis | ferulic acid | Improve microcirculation, anti-platelet aggregation |
| Chuanxiong | Ligustrazine | Dilate blood vessels and relieve spasms |
| white peony root | Paeoniflorin | Analgesic, anti-inflammatory, immune regulation |
| Rehmannia glutinosa | Catalpol | Promote hematopoiesis, antioxidant |
3. Modern applications and precautions
The application of Siwu Decoction has broken through the traditional gynecological scope and expanded toPostoperative anemia, menopausal syndrome, chronic fatigueand other fields. Japanese Kampo research ("Journal of Japanese Medicine") confirmed that it can increase hemoglobin levels by about 15%-20%. However, it needs to be used strictly based on syndrome differentiation: those with heavy menstruation should use Chuanxiong, those with qi deficiency should add Codonopsis and Astragalus, and patients with diabetes should use Rehmannia glutinosa with caution. It is recommended to take it continuously for no more than 3 months and monitor physical changes regularly.
4. Summary and scientific perspective
As the "first prescription for blood syndrome" in traditional Chinese medicine, Siwu Decoction's value lies inDynamically regulate blood production and operation, rather than simply replenishing blood. Modern pharmacology has confirmed its multi-target mechanism of action, but the misunderstanding of "universal blood replenishment" needs to be avoided. Reasonable compatibility and syndrome differentiation are the key to efficacy. It is recommended to use it individually under the guidance of a doctor, combined with dietary maintenance (such as red dates and wolfberry), in order to give full play to the ancient wisdom of "enough blood will eliminate all diseases".
Quote sources:1. "Taiping Huimin Hejiju Prescription" (official medical code of the Song Dynasty) 2. "Journal of Hehan Medicine" 2018 clinical research data 3. Notes on "Traditional Chinese Medicine Prescriptions" by Deng Tietao, a master of traditional Chinese medicine
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