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Liuwei Dihuang Pills
2026-03-22 19:03:32
Liuwei Dihuang Pills: Classic Prescriptions and Applications of Traditional Chinese Medicine
Liuwei Rehmannia Pills is one of the classic prescriptions of traditional Chinese medicine. It is composed of six medicinal materials: Rehmannia glutinosa, Cornus officinalis, Chinese yam, Alisma, Moutan bark, and Poria cocos. It is mainly used to nourish kidney yin and regulate liver and kidney deficiency. This article will expand on its historical origin, main ingredients, applicable symptoms and modern research to help readers fully understand the reasonable application of this traditional Chinese medicine. In terms of content structure, it first outlines its core value, then breaks down the ingredients and efficacy, then discusses the applicable groups and precautions, and finally summarizes its scientificity and practicality.
Historical origins and prescription composition

Liuwei Dihuang Pills originated from the Song Dynasty pediatric treatise "Pediatric Medicine Zhijue". The famous doctor Qian Yihua cut Zhang Zhongjing's "Shenqi Pills" and removed the two yang-warming herbs of aconite and cinnamon twigs, becoming a basic prescription for nourishing kidney yin. Each of its six medicinal materials performs its own duties:Rehmannia glutinosaTonifying the kidneys and replenishing essence is a royal medicine.dogwoodTonifying the liver and strengthening essence,yamIt is a ministerial drug that invigorates the spleen and kidneys.AlismaReducing dampness and purging turbidity,Peony barkClear liver fire,PoriaIt is used as an auxiliary medicine to exude dampness and strengthen the spleen, forming a unique combination of "three tonics and three diarrhea". This recipe embodies the therapeutic wisdom of traditional Chinese medicine of "replenishing without stagnation".
| Medicinal materials | Main functions |
|---|---|
| Rehmannia glutinosa | Nourishes yin and nourishes kidney, replenishes essence and marrow |
| dogwood | Replenishes the liver and kidneys, astringes essence and solidifies ejaculation |
| yam | Nourish the spleen and stomach, promote body fluid and benefit the lungs |
Applicable symptoms and scientific verification
This recipe is traditionally used forKidney yin deficiencyIt causes symptoms such as soreness and weakness in the waist and knees, dizziness, tinnitus, night sweats and spermatorrhea. Modern research shows that it has a certain auxiliary effect on regulating immune function and improving menopausal syndrome. A 2020 study in the journal "Chinese Patent Medicine" pointed out that Liuwei Dihuang Pills can improve chronic fatigue by regulating the hypothalamic-pituitary-adrenal axis (see the table below for data). It should be noted that it is aimed at people with "yin deficiency" constitution, and it should not be used if you have symptoms of yang deficiency such as aversion to cold and cold limbs.
| research indicators | improvement rate | research sample |
|---|---|---|
| chronic fatigue syndrome | 68.3% | 120 cases (randomized controlled trial) |
Reasonable use and precautions
What you need to follow when taking Liuwei Dihuang PillsTreatment based on syndrome differentiationIn principle, it is recommended to use it under the guidance of a traditional Chinese medicine practitioner. You should stop taking it during colds and fever. People with weak spleen and stomach may need to take spleen-strengthening drugs. Modern preparations include pills, capsules, etc. Please refer to the instructions for dosage. According to data from the State Food and Drug Administration, the incidence of adverse reactions is less than 0.1%, but long-term use still requires regular evaluation of physical changes.
Fusion of traditional wisdom and modern values
As a classic prescription that has been around for thousands of years, Liuwei Dihuang Pills embodies the core idea of "balance of yin and yang" in traditional Chinese medicine. From the perspective of modern medicine, its value lies not only in symptom relief, but also in overall conditioning. However, it must be clear that traditional Chinese medicine is not a panacea, and rational use requires a combination of individual constitution and professional guidance. In the future, through more evidence-based medical research, this traditional prescription may provide more scientific support for health management.
Quote sources:
1. "Pharmacopoeia of the People's Republic of China" 2020 Edition
2. Qian Yi's "Pediatric Medicine Syndrome"
3. Zhang Zhongjing's "Synopsis of the Golden Chamber"
4. "Clinical Research on Liuwei Dihuang Pills in the Treatment of Chronic Fatigue Syndrome", Issue 12, 2020 of "Chinese Patent Medicine"
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