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2026-03-23 16:55:32
Yiguanjian: A classic prescription for nourishing yin and soothing the liver.
Yiguanjian is one of the classic prescriptions of traditional Chinese medicine. It was created by Wei Yuhuang, a famous doctor in the Qing Dynasty. Its main function is to nourish yin and soothe the liver. It is suitable for symptoms such as hypochondriac pain, dry throat, dizziness and other symptoms caused by liver and kidney yin deficiency and liver qi discomfort. This article will focus on four aspects: prescription composition, efficacy mechanism, applicable population, and modern applications to help readers fully understand the clinical application value of this traditional prescription.
Prescription composition and compatibility characteristics

Yiguanjian is composed of six medicinal herbs: Adenophora adenophora, Ophiopogon japonicus, Angelica sinensis, Rehmannia glutinosa, Lycium barbarum, and Soupelandia too, which embodies the therapeutic idea of "nourishing water and nourishing wood". Among them, Rehmannia glutinosa and Lycium barbarum are the main medicines to nourish the yin of the liver and kidneys; Adenophora adenophora and Ophiopogon japonicus are supplementary medicines to nourish yin and promote fluid production; Angelica sinensis nourishes and activates blood circulation, and Sophora azadirachta root soothes the liver and regulates qi. This combination not only replenishes liver yin but also soothes liver qi, taking into account both the symptoms and root causes, and embodies the therapeutic wisdom of "tonifying without stagnation" of traditional Chinese medicine.
Efficacy mechanism and key points of syndrome differentiation
This prescription mainly works by nourishing the yin fluid of the liver and kidneys and relieving the stagnation of liver qi. It is suitable for typical syndromes of yin deficiency and liver stagnation such as red tongue, less fluid, stringy and thin pulse. Modern research shows that the medicine in the prescription has the effects of regulating endocrine, improving microcirculation, and anti-inflammatory. Clinically, dull pain in the flanks, dry throat and mouth, and irritability and irritability are the main syndrome differentiation points. However, it should be noted that it is not suitable for use with damp-heat syndrome and yang deficiency syndrome.
Modern applications and considerations
In modern clinical practice, Yiguanjian is widely used in patients with chronic hepatitis, gastritis, menopausal syndrome, etc. who suffer from yin deficiency and liver stagnation. When using it, additions and subtractions should be made according to specific symptoms: for rib pain, add Curcuma and Corydalis; for yin deficiency, add Dendrobium and Polygonatum odorifera. It is recommended to use it under the guidance of a physician and avoid self-medication. Avoid spicy food while taking the medicine, and maintaining a comfortable mood can enhance the curative effect.
Summary and Outlook
As a representative prescription for nourishing yin and soothing the liver, Yiguanjian embodies the concept of "treating the disease based on the root cause" of traditional Chinese medicine. Its prescription is accurate and its efficacy is clear, and it still has important clinical value in the contemporary era. With the deepening of modern research, its mechanism of action will become clearer and its scope of application is expected to be further expanded, bringing health and well-being to more patients.
| Main ingredients | Efficacy | Dosage (g) |
|---|---|---|
| North Adenophora | Nourishing yin and clearing the lungs | 9-12 |
| Ophiopogon japonicus | Nourishing yin and promoting fluid production | 9-12 |
| Angelica sinensis | Replenish blood and activate blood circulation | 6-9 |
| Rehmannia glutinosa | Nourishing yin and nourishing blood | 12-15 |
| wolfberry | Nourishes liver and kidneys | 9-12 |
| Sophora azadirachta | Soothe the liver and regulate qi | 4.5-6 |
Quote sources:"Continuation of Famous Medical Cases" Wei Zhixiu (Wei Yuhuang)/"Traditional Chinese Medicine Prescriptions" New Century Fourth Edition Textbook/Clinical efficacy data comes from "Chinese Materia Medica"
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