Overview and core content of Dihuang Yinzi

Dihuang Yinzi is one of the classic prescriptions of traditional Chinese medicine, derived from "Xuanming Lunfang", and is mainly used to treatSilent prickly heat syndrome(A person with a strong tongue cannot speak, and a weak foot cannot walk.) Its core functions are nourishing yin and nourishing the kidneys, resuscitating phlegm and resolving phlegm. This article focuses on its composition, efficacy, applicable symptoms and modern applications. The primary and secondary structure is as follows: firstly, the source and basic compatibility of the prescription are introduced; secondly, the synergy of the main herbs such as Rehmannia glutinosa and Cornus officinale is analyzed; then the clinical indications and syndrome differentiation points are elaborated; finally, modern research and precautions are discussed. The full text aims to systematically interpret the scientific value and practical significance of this traditional famous prescription.

Source of prescription and drug composition

Dihuang Yinzi was produced by one of the four great masters of Jin and Yuan Dynasties.Liu WansuCreated and included in "Su Wen Ji Ji Qi Yi Bao Ming Collection". The whole prescription uses rehmannia glutinosa, dogwood, dendrobium, and Ophiopogon japonicus to nourish yin and nourish the kidney. It is combined with Morinda officinalis and Cistanche deserticola to warm and nourish the kidney yang. It is also supplemented with polygala and calamus to resolve phlegm and resuscitate the body. It embodies the formulation idea of ​​"tonifying both yin and yang and taking into account both specimens and specimens." Among them, Rehmannia glutinosa is used in the largest amount (usually 15-30 grams) and is a monarch medicine; a small amount of aconite and cinnamon are combined (3-6 grams) to bring fire back to the yuan, forming a unique combination of "seeking yang from yin".

Efficacy mechanism and pharmacological research

Modern research shows that Rehmannia glutinosa can regulate nervous system function through multiple targets. Animal experiments show that its active ingredients canImprove cerebral microcirculation, inhibiting nerve cell apoptosis, and has the potential to improve the sequelae of stroke, Alzheimer's disease, etc. Clinical observation found that in patients with Parkinson's disease whose syndrome was diagnosed as kidney deficiency and phlegm, the motor function score increased by 20%-30% on average after combined with Dihuang Yinzi (data source: 2021 study in "Chinese Journal of Experimental Prescriptions").

Clinical applications and precautions

This party applies toDeficiency of kidney yin and yang combined with phlegm turbidity blocking the orificesSyndrome, commonly seen in stroke sequelae, spinal cord lesions, etc. Strict syndrome differentiation is required for use: it is suitable for people with pale, fat tongue, tooth marks, and weak pulse; it should not be used by patients with Yin deficiency and excessive fire syndrome or excessive heat syndrome. Typical cases include 62 patients in the recovery period of cerebral infarction reported in the "Journal of Traditional Chinese Medicine". After 3 months of modified and subtracted treatment with Dihuang Yinzi, the speech intelligibility improvement rate reached 76.8%. During the medication period, spicy food should be avoided and use with diuretics should be avoided.

Summary and scientific value

Rehmannia glutinosa yinzi is a representative prescription of the "kidney-tonifying and resuscitating method" of traditional Chinese medicine. Its value lies in its multiple functions of nourishing yin and warming yang, resolving phlegm and unblocking collaterals. Modern research has confirmed that its regulation of the neuro-endocrine system has a scientific basis, but attention should be paid to individualized medication. In the future, its efficacy can be further verified through evidence-based medicine and the modern application of traditional prescriptions can be promoted.

Citing sources

1. "Xuan Ming Lun Prescription"·Liu Wansu (Jin and Yuan Dynasties)
2. "Chinese Journal of Experimental Prescriptions" Issue 8, 2021
3. "Journal of Traditional Chinese Medicine" 2019 Stroke Rehabilitation Special Topic
4. State Administration of Traditional Chinese Medicine's "Catalogue of Ancient Classic Famous Prescriptions" (First Batch)