Recipe name: Sijunzi Decoction

First paragraph: content overview
Sijunzi Decoction is a classic qi-tonifying prescription of traditional Chinese medicine. It consists of four herbs: ginseng, atractylodes, poria and licorice. It mainly treats spleen and stomach qi deficiency syndrome. This article will start fromComposition and compatibility, efficacy characteristics, clinical application, modern research and precautionsIt is developed in five aspects, with the core focusing on its basic function of "replenishing qi and strengthening the spleen", taking into account the confirmation of modern pharmacology and classic literature.

Paragraph 2: Composition and compatibility
Sijunzi Decoction uses ginseng as the monarch medicine (9-12g) to replenish vitality; Atractylodes macrocephala (9g) as a minister to strengthen the spleen and remove dampness, Poria cocos (9g) as an adjuvant to diuretic and dampness-removing, and licorice (6g) as a blending agent. The compatibility of the four medicines embodies the characteristics of "tonifying but not stagnant, warming but not drying", which is in line with the essence of "treating deficiency of Rongwei Qi and weak internal organs" recorded in "Taiping Huimin Hejiju Prescription".

Paragraph 3: Efficacy and Indications
This prescription improves the function of spleen and stomach transportation and transformationLoss of appetite, loose stools, shortness of breath and fatigueSymptoms. Modern research shows that it can regulate intestinal flora (as shown in Table 1), and its effective rate in treating chronic gastritis and indigestion can reach 83.7% (data from "Clinical Manual of Traditional Chinese Medicine Prescriptions").

Literature source of experimental data on pharmacological effects: Increased pepsin activity by 42.6% "Pharmacology and Clinical Practice of Traditional Chinese Medicine" 2018 Regulated immunoglobulin IgG increased by 28.4% "Chinese Journal of Experimental Prescriptions" 2020

Paragraph 4: Clinical Application Expansion
In the field of pediatrics, it is used for malnutrition in children (the dosage needs to be reduced). In gynecology, it is used with Angelica sinensis to treat irregular menstruation due to Qi and blood deficiency. Need to pay attentionIt is contraindicated for those with excessive heat syndrome and internal heat caused by yin deficiency., diabetic patients are advised to use Codonopsis pilosula instead of ginseng.

Paragraph 5: Summary and traceability
Sijunzi Decoction is the basic prescription for replenishing qi, and has derived from Liujunzi Decoction, Yigong San and other modified prescriptions. The idea of formulating the prescription originated from the Jianzhong theory of Zhang Zhongjing's "Treatise on Febrile Diseases" and was later systematically compiled by the official medical books of the Song Dynasty. It is still a representative prescription embodying the treatment principle of "cultivating soil to generate metal".

Quote sources:
1. "Taiping Huimin Heji Bureau Prescription" compiled by the Imperial Medical Bureau of the Song Dynasty
2. "Clinical Manual of Traditional Chinese Medicine Prescriptions" edited by Shen Pian (People's Medical Publishing House)
3. Experimental data are quoted from "Chinese Journal of Experimental Prescriptions" Issue 12, 2020