Xuefu Zhuyu Decoction: Analysis of the classic prescription for promoting blood circulation and removing blood stasis.

Xuefu Zhuyu Decoction is a classic prescription recorded in "Yi Lin Gai Cuo" by Wang Qingren, a famous doctor in the Qing Dynasty. It has the main functions of promoting blood circulation and removing blood stasis, promoting qi and relieving pain. It is often used to treat blood stasis in the chest and ribs, headaches, palpitations and other syndromes of qi stagnation and blood stasis. This article will start from the prescription composition, indications, modern applications and precautions, and analyze its clinical value clearly. The core content is in order: the origin and compatibility characteristics of the prescription, the key points of syndrome differentiation of the main symptoms, scientific verification of modern research, and contraindications for use and compatibility.

1. Origin and compatibility characteristics of prescriptions

Xuefu Zhuyu DecoctionPeach kernel, safflower, angelica, rehmannia glutinosa, chuanxiong, red peony root, achyranthes root, platycodon, bupleurum, citrus aurantium, licoriceIt is composed of 11 medicinal herbs, including peach kernel and safflower as the monarch herbs, which can activate blood circulation and remove blood stasis; Bupleurum and Citrus aurantium soothes the liver and regulates qi, embodying the traditional Chinese medicine theory that "the movement of qi leads to the movement of blood". Wang Qingren proposed the concept of "Xuefu", which is blood stasis in the chest. This prescription targets typical symptoms such as tingling in the chest and hypochondrium, irritability and irritability by harmonizing Qi and blood. Modern pharmacological research shows that its active ingredients can improve microcirculation and inhibit platelet aggregation (citation source: Wang Qingren in "Yilin Gaicuo").

2. Main symptoms and key points of syndrome differentiation

This party applies toQi stagnation and blood stasis syndrome, the common symptoms are chest pain like pins and needles, fixed, or persistent headache, insomnia and dreaminess, dark purple tongue or ecchymosis. Clinically, it is commonly used for patients with coronary heart disease, angina pectoris, migraine, menopausal syndrome, etc. who suffer from internal blood stasis. It is necessary to pay attention to distinguish it from Qi deficiency and blood stasis or cold coagulation and blood stasis syndrome. The latter needs to be combined with Yang-warming drugs. The following table lists clinical observation data for some indications:

3. Modern applications and precautions

Modern medicine has expanded Xuefu Zhuyu Decoction toGynecological irregular menstruation,post-traumatic bruisingand other fields, but strict identification is required. It is prohibited for pregnant women and patients with bleeding disorders; combined use with anticoagulants may increase the risk of bleeding. It is recommended to adjust the dosage under the guidance of a physician. For those with severe blood stasis, add Salvia miltiorrhiza, and for those with obvious qi stagnation, add Cyperus rotunda. Typical cases show that combined treatment with western medicine can reduce the recurrence rate of angina pectoris (citation source: "Chinese Journal of Traditional Chinese Medicine" 2021).

Summary: Combination of inheritance and scientific verification

As a representative prescription for promoting blood circulation and removing blood stasis, Xuefu Zhuyu Decoction has a deep foundation in traditional theory and its efficacy has been confirmed by modern research. When using it, you should closely follow the pathogenesis of "blood stasis" and avoid abuse or long-term use. In the future, it is necessary to further clarify its mechanism of action through large-sample studies to promote the international development of traditional Chinese medicine (comprehensive citation: "Yilin Correction", Chinese Pharmacopoeia 2020 Edition).